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4-Pentynoic acid (Propargylacetic acid) is an intermediate to produce biologically active compounds 4-Pentynoic acid is widely utilized as a building block for the synthesis of eight sequence-defined model oligomers[1] 4-Pentynoic acid is a click chemistry reagent it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
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Pentynoic acid STP ester sodium is a water-soluble, alkyne-activated STP (sulfotetrafluorophenyl) ester reagent used to introduce a terminal alkyne handle onto proteins and peptides for bioconjugation. It enables amine-targeted coupling under mild, aqueous conditions and subsequent alkyne-based conjugation such as copper(I)-catalyzed azide-alkyne cycloaddition.
Contains a terminal propargyl (alkyne) group for click chemistry.
STP activated ester enables efficient coupling to lysine residues.
Water-soluble formulation suitable for reactions in aqueous buffers.
High purity for reproducible bioconjugation outcomes.
DMSO-soluble at high concentration; ultrasonication may be required.
Store sealed and away from moisture to preserve reagent activity.
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NSC 8751 (trans-2-Butenoic acid trans-Crotonic acid) is an unsaturated carboxylic acid compound containing -unsaturated carboxylic acid groups NSC 8751 is one of the important analogs for evaluating the safety of fragrance ingredients and is used to evaluate the toxicological properties of compounds with similar structures When NSC 8751 is applied to local lymph nodes a 50% concentration does not cause skin sensitization Structural analogs of NSC 8751 have been shown to be non-genotoxic trans-Crotonic acid can be used in the preparation of cosmetics and food additives[1][2]
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2-Methyl-4-pentenoic Acid is an organic acid that can be used as a precursor for synthesizing other compounds. Additionally, changes in the level of 2-Methyl-4-pentenoic Acid may be associated with the susceptibility to schizophrenia and type 2 diabetes. This product is for research use only.
Liquid appearance (density: 0.956 g/cm3)
Colorless to light yellow
SMILES: C=CCC(C)C(O)=O
Classified as ketones, aldehydes, and acids
Initial source: Plants other families
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Inhibits HDAC activity much more potently (IC50 = 13 µM) than valproic acid (IC50 = 398 µM); induces histone hyperacetylation in cerebellar granule cells significantly at 5 µM; induces the expression of Hsp70-1a and Hsp70-1b and protects cerebellar granule cells from glutamate-induced excitotoxicity
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